Acid-reflux disease: Adults: Long-term management, 10 mg od, increasing to 20 mg od if symptoms return.
Duodenal ulcer: Adults: 20 mg od x 4 weeks. Severe cases, increasing to 40 mg od. Prevention of relapse, 10 mg od, increasing to 20 mg od if symptoms return.
DU with H. pylori: Adults: 40 mg od with amoxicillin 1.5-2 gm od x 2 weeks.
Gastric ulcer: Adults: 20 mg od x 8 weeks. Severe cases, increase to 40 mg od.
Zollinger-Ellison syndrome: Adults: 60 mg od adjusted to response. Usual maintenance, 20-120 mg daily. Doses over 80 mg daily, give in bid doses.
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