Salt: Fluconazole
Therapeutic Description: Antifungals, Systemics
Category: Triazole antifungal.
Pregnancy: Contraindicated in pregnancy.
Lactation: Contraindicated or not recommended.
Precautions: Renal impairment.
See under dosage.
Vaginal candidiasis and candidal balanitis: Adults: ORALLY, a single dose of 150 mg.
Mucosal candidiasis (except genital): Adults: ORALLY, 50 mg daily (100 mg daily in unusually difficult infections) given for 7-14 days in oropharyngeal candidiasis (maximum 14 days except in severely immunocompromised patients); for 14 days in atrophic oral candidiasis associated with dentures; for 14-30 days in other mucosal infections (e.g. oesophagitis, candiduria, non-invasive bronchopulmonary infections). Children: ORALLY or by IV infusion, 3-6 mg/kg on first day then 3 mg/kg daily (every 72 hours in neonates up to 2 weeks old, every 48 hours in neonates of 2-4 weeks old).
Tinea pedis, corporis, cruris, versicolor and dermal candidiasis: Adults: ORALLY 50 mg daily for 2-4 weeks (for up to 6 weeks in t
IV: Fluconazole be administered by IV Infusion over approx 1-2 hours; do not exceed 200 mg/hour when giving IV Infusion. Standard diluent: 200 mg/100 mL NS (premixed); 400 mg/200 mL NS (premixed).
Anticoagulants, oral sulfonylureas, phenytoin, cisapride, rifampicin, rifabutin, cyclosporin, astemizole, zidovudine, other drugs metabolised by P450, benzodiazepines.
GI upset, headache, rash.
Strength Pack Size PKR
150 mg1's150.00

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